The novel coronavirus 2019 (COVID-19) pandemic is rapidly advancing across the globe despite drastic public and personal health measures. Antivirals and nutritional supplements have been proposed as potentially useful against SARS-CoV-2 (virus that causes COVID-19), but few have been clinically established.

Lactoferrin (Lf) is a naturally occurring and non-toxic glycoprotein that is orally available as a nutritional supplement and has established in vitro anti-viral efficacy against a wide range of virus including SARS-CoV, a closely related corona virus to SARS-CoV-2 (virus that causes COVID-19). Furthermore, Lf possesses unique immunomodulatory and anti-inflammatory effects that may be especially relevant to the pathophysiology of severe COVID-19 cases.

We review the underlying biological mechanisms of Lf as an antiviral and immune regulator, and propose its unique potential as a preventative and adjunct treatment for COVID-19. We hope that further research and development of Lf nutritional supplementation would establish its role for COVID-19.

Read more: https://www.sciencedirect.com/science/article/pii/S0924857920303010

Per maggiori approfondimenti : 

- https://scienzaonline.com/medicina/item/2621-una-risposta-contro-il-covid-19-la-glicoproteina-lattoferrina,-una-componente-dell%E2%80%99immunit%C3%A0-innata.html

- https://scienzaonline.com/scienceonline-news/item/2597-lactoferrin-as-protective-natural-barrier-of-respiratory-and-intestinal-mucosa-against-coronavirus-infection-and-inflammation.html

- https://scienzaonline.com/medicina/item/2672-ricerca-dati-a-confronto-covid19-colpisce-anche-la-tiroide.html

- https://scienzaonline.com/scienceonline-news/item/2661-immunoprotein-impairs-sars-cov-2.html